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Overall, current evidence suggests that the benefits of GLP-1 treatment are closely linked to ongoing use, and stopping is often followed by a gradual return towards previous physiological levels

Seek urgent medical help for severe abdominal pain, repeated vomiting, signs of dehydration, fainting, swelling of the face or throat, or symptoms of severe low blood sugar

The results suggested that at week 12 after treatment discontinuation, there was no significant difference in weight regain between significant and not significant weight loss subgroup ( P = 0.99) (Additional file 2: Fig

Whether that translates to clinically meaningful improvements in body composition outcomes when added to tirzepatide specifically is what remains unproven

The Role of B12 in Metabolism Vitamin B12 helps convert fat and protein into energy, supporting healthy metabolic function